Multi-channel Ultrasonic Cell Disruptors Can Increase Sample Processing Efficiency Dozens Of Times.

Sep 08, 2025

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Ultrasonic Principle

In liquids, physical effects such as eddy currents or ultrasound create temporary localized negative pressure zones, generating bubbles (also called cavities, holes, or cavitation bubbles) within the liquid. These bubbles can be filled with gas, steam, or vacuum, and can range in size from microns to visible to the naked eye. Their lifespans vary, and the generation of cavitation bubbles and their resulting effects on the medium are called cavitation.

Multi-channel ultrasonic cell disruptors

When the negative pressure of sound waves propagating through a liquid reaches a certain level, visible bubbles form within the liquid. Cavitation bubbles expand and contract with the sound waves. When they violently collapse, they generate extreme temperatures and pressures within, generating acoustic microstreaming, jets, and shock waves. This sound-induced cavitation phenomenon and effect is called acoustic cavitation, also known as ultrasonic cavitation.

Common probe-type (contact) ultrasonic instruments utilize a single transducer and horn, processing only one sample at a time. However, this is insufficient for large-scale, high-throughput screening during research. Therefore, SCIENTZ independently developed a single-transducer, multi-amplifier, multi-channel ultrasonic cell disruptor, customizable from 2 to 96 channels-yes, up to 96 channels! It can process a 96-well plate of samples at once, which might have taken 5 x 96 = 480 minutes. Now, it takes only 5 minutes! With the remaining 475 minutes, you can conduct more experiments.

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